[Microbiology] Atlas about Antibiotic Mechanisms of Action and Resistance

Atlas about Antibiotic Mechanisms of Action and Resistance, Antibiotic Mechanisms of Action and Resistance, Antibiotic , Mechanisms, of, Action, and, Resistance, atlas in medical, tuyenlab.net

Fig 1.  Primary sites of antibacterial action for major classes of antimicrobial agents. THFA, Tetrahydrofolic acid; DHFA, dihydrofolic acid; PABA, para-aminobenzoic acid.

Fig 2.  The cell envelope structure of a gram-positive (left) and a gram-negative
(right) bacterium.

Fig 3.  A diagram that demonstrates the structure of the peptidoglycan layer in
the cell wall of Escherichia coli. The amino acids in the cross-linking tetrapeptides may
vary among species. NAG, N-acetyl-D-glucosamine; NAM, N-acetyl-D-muramic acid.

Fig 4.  Chemical structures of major classes of β-lactam antibiotics.

Fig 5.  Sites of action of sulfonamides and trimethoprim and their effects on synthesis of essential
amino acids and nucleic acids.

Fig 6.  Active efflux in gram-negative bacteria mediated by transmembrane proteins located in cytoplasmic and outer membrane. Emr/Mex, Multidrug transporter efflux system; ABC ATPase, ATP-binding cassette family pumps; ATP, adenosine triphosphate; ADP, adenosine diphosphate;
Tet A, tetracycline specific transporter pump; H+, efflux pumps driven by proton motive force mediated by the counterflow of protons.

Fig 7.  β-Lactamase hydrolyzes the β-lactam ring portion of the penicillin molecule. The hydrolysis results in the formation of penicilloic acid, which does not have antibacterial activity.

This is a part of the book : Textbook of Diagnostic Microbiology 4th edition 2011 of authors: Connie R. Mahon, Donald C. Lehman and George Manuselis. If you want to view the full content of the book and support author. Please buy it here: http://amzn.to/2ctxo02